CResPace is a H2020 consortium of 8 academic and industrial partners which develops adaptive bioelectronics. One application area of the methodology we are developing is adaptive cardiac resynchronization. The technology relies on small neural networks known as central pattern generators that respond to physiological feedback in real time to provide realistic pacing. CResPace is working to extend patient’s life and quality of life.
The technology mimics the function of medullary neural circuits located at the base of the brain which regulate cardiac function by responding to changes in physiological feedback. These circuits, known as Central Pattern Generators (CPGs), are small neural networks which control respiration and heart rate, the coordination between muscles responsible for swallowing. We implement these central pattern generators using physical hardware to replicate natural control of heart rate and re-synchronize heart chambers.
University of Bristol, Physiology
Prof Julian Paton
University of Zurich, Neuromorphic Engineering
Prof Giacomo Indiveri
Mr Tracy Wotherspoon
Dr Berthold Steggemann
University of Vienna, Cardiology
Prof Mariann Gyongyosi
University of Utrecht, Physiology
Prof Marc Vos
International Clinical Research Centre, Brno
Dr Viola Galligioni